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  • Differentiate between rough and smooth endoplasmic reticulum. How is endoplasmic reticulum important for membrane biogenesis?

Differentiate between rough and smooth endoplasmic reticulum. How is endoplasmic reticulum important for membrane biogenesis?

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Answer:

Differences between Rough Endoplasmic Reticulum & Smooth Endoplasmic Reticulum.

Rough Endoplasmic Reticulum

Smooth Endoplasmic Reticulum

Rough Endoplasmic Reticulum has ribosomes on its surface.

Smooth Endoplasmic Reticulum lacks ribosomes and this is the reason they are known as smooth endoplasmic reticulum.

Rough Endoplasmic Reticulum is in vesicular and tubular form.

Smooth Endoplasmic Reticulum has flattened sacs known as cisternae.

Rough Endoplasmic Reticulum is present more around nucleus therefore deep in cytoplasm

Smooth Endoplasmic Reticulum is present close to cell membrane than nucleus so these are not deep in cell.

Rough Endoplasmic Reticulum main function is to synthesize proteins and enzymes.

Smooth Endoplasmic Reticulum is involved in synthesis of lipids glycogen and steroids.

Role of smooth endoplasmic reticulum and rough endoplasmic reticulum: In cell membrane, mainly made up of lipids (40-45%) and proteins (50-60%), endoplasmic reticulum with ribosomes is actively involved in synthesis of proteins and enzymes. Smooth endoplasmic reticulum is involved in the synthesis of lipids which are the key constituents of cell membrane. This is how rough endoplasmic reticulum and smooth endoplasmic reticulum helps in building cell membrane.

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