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  • Illustrate the design of a bioreactor. Highlight the difference between a flask in your laboratory and a bioreactor which allows cells to grow in a continuous culture system.

Illustrate the design of a bioreactor. Highlight the difference between a flask in your laboratory and a bioreactor which allows cells to grow in a continuous culture system.

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(a) Simple stirred-tank bioreactor;
(b) Sparged stirred-tank bioreactor through which sterile air bubbles are sparged

Structure of Bioreactor:

  1. It is a cylindrical structure with a curved base.
  2. A stirrer is present for even mixing and oxygen availability throughout the reactor.
  3. There is an agitator system, an oxygen delivery system, a foam control system, a temperature control system, etc.
  4. There is a sampling port through which small volumes of culture can be taken out periodically.

A flask in a laboratory cannot be used for producing recombinant DNA on a large scale. Unlike a bioreactor: a flask cannot be used to grow culture continuously.

Posted by

Gurleen Kaur

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