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Based on your understanding of genetic code, explain the formation of any abnormal haemoglobin molecule. What are the known consequences of such a change?

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Normally human beings have following types of haemoglobin:  HbA , HbA2 and HbF. Alteration in genes for the beta chain on haemoglobin results in the formation of HbS type of haemoglobin. This type of haemoglobin molecule is responsible for sickle cell anaemia.

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