The total number of genes in humans is far less (< 25,000) than the previous estimate (up to 1,40,000 gene). Comment.
When scientists began estimating the number of human genes, they began with a very high figure, i.e. more than 100,000. At that time, the technology for studying human genes was not sophisticated or advanced enough, and the estimate was qualitative in nature as it was mainly based on assumptions. With the gradual progress of technology and knowledge about the human genes, the estimated number began to come down. The present knowledge tells us that the total number of genes in humans is between 20,000 to 25,000.