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  • A single base mutation in a gene may not 'always' result in loss or gain of function. Do you think the statement is correct? Defend your answer.

 A single base mutation in a gene may not 'always' result in loss or gain of function. Do you think the statement is correct? Defend your answer.

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. A single base mutation in a gene may not always result in loss or gain of function. We know that a codon Is composed of three nucleotides. In simplified terms, a codon can be taken as a word, which is composed of 3 letters. For making any meaningful sentence, we need a complete word. Addition or deletion of a single letter may not result In a meaningful word. Hence, in most of the cases, there is a need for a mutation in three bases to affect loss or gain of function. This can be illustrated by the following example of a sentence being altered:

RAM HAS RED CAP

 RAM HAS BRE DCA P

 RAM HAS BIR EDC AP

 RAM HAS BIG RED CAP

It is quite clear that a meaningful sentence is made only when at least three letters are inserted in this sequence.

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