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  • Discontinuous synthesis of DNA occurs in one strand, because: a. DNA molecule being synthesised is very long b. DNA dependent DNA polymerase catalyses polymerisation only

Discontinuous synthesis of DNA occurs in one strand, because:

a. DNA molecule being synthesised is very long

b. DNA-dependent DNA polymerase catalyses polymerisation only in one direction (5' → 3')

c. it is a more efficient process

d. DNA ligase joins the short stretches of DNA

Answers (1)

The answer is the option (b) DNA-dependent DNA polymerase catalyses polymerisation only in one direction (5' -> 3')

Only one pathway of polymerisation (5′ to 3′) is catalysed by DNA-dependent DNA polymerase. At the replication fork, this results in further problems. Replication is therefore discontinuous on one strand (5′ → 3′) and continuous on the other (3′ → 5′). Later, the pieces that were synthesised irregularly are joined by the DNA ligase enzyme. Hence. (b) is the correct option.

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