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DNA is a polymer of nucleotides which are linked to each other by 3'-5’ phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose?

a. Replace purine with pyrimidines

b. Remove/Replace 3′ OH group in deoxyribose

c. Remove/Replace 2′ OH group with some other group in deoxy ribose

d. Both 'b' and 'c'

Answers (1)

The answer is the option (b) Remove/replace 3' OH group in deoxyribose

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