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C-peptide of human Insulin is:
a. A part of mature insulin molecule
b. Responsible for formation of disulphide bridges
c. Removed during maturation of pro-insulin to insulin
d. Responsible for its biological activity
Answers (1)
c). Removed during maturation of pro-insulin to insulin
The connecting peptide or C-peptide is a short protein containing 31 amino acids. It connects the A and B chain of proinsulin molecule. After the processing of proinsulin molecule, C-peptide is removed leaving behind A and B chains which bound together by disulphide bonds to constitute an insulin molecule.
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