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Give an account of post-transcriptional modifications of a eukaryotic mRNA.
Answers (1)
The following events happen during the transformation of hnRNA (precursor of mature mRNA):
- Polymerase II facilitates the transcription of hnRNA into mature mRNA,
- Primary transcripts contain both the introns and exons and these are non-functional. Splicing takes place which results in the removal of introns and the joining of exons in the defined order.
- Capping and tailing happen in hnRNA. It acquires a cap of methyl guanosine and a tail of polyadenylate. Cap Is added at the 5' end, and Poly-A tail is added at the 3' end of hnRNA.
- Now, the hnRNA changes into mature mRNA.
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