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How was Insulin obtained before the advent of rDNA technology? What were the problems encountered?
Answers (1)
Before the advent of rDNA technology, Insulin was mainly obtained from the pancreas of slaughtered animals. This often resulted in unwanted side effects on the users such as -
Allergic Reactions: Insulin derived from animals sometimes triggers allergic responses in patients because of slight structural differences between animal insulin and human insulin.
Cost and Ethical Concerns: The extraction of animal insulin was expensive and brought up ethical issues related to the widespread killing of animals for medical use.
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