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Recall the experiments done by Frederick Griffith, Avery, MacLeod and McCarty, where DNA was speculated to be the genetic material. If RNA, instead of DNA was the genetic material, would the heat-killed strain of Pneumococcus have transformed the R-strain into virulent strain? Explain.

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RNA is less stable than DNA, and hence, DNA replaced RNA as the genetic material in the living world. If RNA was the genetic material in Griffith's experiment, it would have been destroyed by heat. Thus, the heat-killed strain of Pneumococcus could not have transformed the R-strain into a virulent strain.

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