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What is the function of histones in DNA packaging?
Answers (1)
Histones are proteins that play a crucial role in DNA packaging by helping to organize and compact DNA within the nucleus of a cell. Histone acts like a spool around which DNA is wrapped. The major functions are:
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Structural Support: Histones bind to DNA, forming a complex called nucleosomes, which resemble "beads on a string." Each nucleosome consists of a core of histone proteins wrapped with DNA, helping to organize the long DNA strands into a more compact structure.
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Regulation of Gene Expression: The way DNA is wrapped around histones can affect gene accessibility. Acetylation, methylation, and other modifications of histones can either relax or tighten the DNA, regulating whether specific genes are turned on or off.
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