During deficiency of oxygen in tissues of human beings, pyruvic acid is converted into lactic acid in the
(a) cytoplasm
(b) chloroplast
(c) mitochondria
(d) golgi body
Ans. (a)
The pyruvate formed from glycolysis goes into the Kreb's cycle as acetyl co-enzyme and creates a pool of chemical energy (ATP, NADH and FADH2). One of the substitute destinies of pyruvic acid in cellular respiration is that it can be changed over into lactic acid. This regularly happens in the cytoplasm of solid tissue under exhausting condition. Hence Pyruvic acid is converted into lactic acid in the cytoplasm of muscle cells during deficiency of oxygen in human beings.
Therefore option (A) is correct